Analysis on non-invasive fungal rhinosinusitis for 59 cases by endoscopic sinus surgery / 临床耳鼻咽喉头颈外科杂志

OBJECTIVE@#To explore the etiology and clinical features of non-invasive fungal rhinosinusitis and to evaluate the methods and curative effects of endoscopic sinus surgery.@*METHOD@#The denial and follow-up data of 59 patients with non-invasive fungal rhinosinusitis were retrospectively analyzed.@*RESULT@#Following up for 2-5 years, no complications were observed. Fifty-seven patients were cured and two cases were recurred.@*CONCLUSION@#Clearing up the infected focus by endoscopic sinus surgery is an effective treatment of non-invasive fungal rhinosinusitis. Enlarging the opening of cavity during the operation, the regular irrigation and rechecking after the operation were important for avoiding the recurrence.

Change of ACTH and cortisol in patients with obstructive sleep apnea hypopnea syndrome after the operation of uvulopalatopharyngoplasty / 临床耳鼻咽喉头颈外科杂志

OBJECTIVE@#To explore the change of hypothalamus-pituitary-adrenal hormone in patients with Obstructive sleep apnea hypopnea syndrome (OSAHS) by observing the change of Corticotropin (ACTH) and cortisol after Uvulopalatopharyngoplasty (UPPP).@*METHOD@#OSAHS patients were monitored by polysomnography (PSG). The ACTH and cortisol levels in plasma were measured by radioimmunoassay before, during and after sleep in pre-operation and six months post-operation. Their correlation were analyzed.@*RESULT@#The cortisol concentration [ (170.4+/-56.5) microg/L, (252.2+/-62.3) microg/L, (276.9+/-70.4) microg/L, (2859.0+/-63.2) microg/L, (395.1+/-85.2) microg/L before, during and after sleep] in the before UPPP group were significantly higher than those of the after UPPP group [(133.5+/-24.8) microg/L, (99.9+/-9.2) microg/L, (103.8+/-13.2) microg/L, (146.2+/-22.5) microg/L, (199.6+/-20.9) microg/L before, during and after sleep, respectively, all P <0. 05]; but there was no difference in corticotropin(ACTH). The average blood oxygen concentration was negatively correlated with average awareness duration (r = -0.713).@*CONCLUSION@#There are abnormal change of HPA axis in OSAHS patients, and the feedback regulation is disordered. These abnormalities are related to sleep awareness and hypoxia during sleep.